Angie Muhammad had been receiving treatment at Northwestern Memorial Hospital since December 2003. She was hospitalized four times between January and May 2005 with psychotic symptoms.
In May 2005, she was prescribed Depakote as a mood stabilizer.
She became pregnant. After being advised by her physician, she discontinued using Depakote in October 2005. However, between May and October 2005 she received increasingly large doses of Depakote. Her child, C.M., was born with severe spina bifida, a known potential side effect from exposure to Depakote in utero.