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Early Diagnosis of Neonatal Sepsis

In an article presented by the Journal of Pediatric Infectious Diseases, the abstract of the article states that sepsis is one of the most significant contributors to mortality and morbidity in the neonatal population. The need to find specific biomarkers that provide meaningful information about the diagnosis of sepsis in neonatals is ongoing. The article calls out the study aimed to investigate the utility of N-terminal pro b-type natriuretic peptide (NT-proBNP) as a diagnostic biomarker in newborn infants with late-onset sepsis. This marker is associated with blood volume and pressure and with the work that the heart must do in pumping blood throughout the body. The marker is primarily used to help detect, diagnose and evaluate the severity of heart failure. BNP is a hormone produced by the heart. Levels go up when heart failure develops or gets worse, and levels go down when the heart failure is stable. The marker of cardiac dysfunction is associated with sepsis in preterm neonates.

The increased levels of B-type natriuretic peptide (BNP) and N-terminal prohormone of brain natriuretic peptide (NT-proBNP) are related with the dysfunction of a cardiovascular system and systemic inflammation.

In the study that was done, it included 87 patients diagnosed with sepsis and 35 controlled patients. The median NT-proBNP were higher in septic patients showing a significant correlation in measuring white blood cell count, serum C-reactive proteins (CRP), plasma interleukin and whole blood levels.

In conclusion, plasma NT-proBNP levels were higher in septic neonates.

If you or someone you know or love has been injured or died in labor, or as defined as a maternal death, Kreisman Law Offices is prepared to handle your case. Robert Kreisman of Kreisman Law Offices has more than 40 years of experience and has been successfully handling maternal death cases.

Kreisman Law Offices has prevailed in trials and settlements in Chicago, Illinois and its surrounding areas and successful resolved cases for birth injury lawsuits, wrongful death claims and maternal death cases for these many years.

With our years of experience in trying and settling birth trauma injury cases, maternal death cases and wrongful death matters, Kreisman Law Offices provides the best possible services to our clients and have achieved unsurpassed results. Our service is unmatched. Please call us 24 hours a day at 312-346-0045 or toll free 800-583-8002 for a free and immediate consultation or complete a contact form online on our website.

Client Reviews
★★★★★
“We were devastated when our 31 year-old son was killed by a negligent driver. Kreisman Law Offices did everything to help us through this very difficult time, including coming out to the house several times which was a comfort. My wife and I were extremely pleased with Mr. Kreisman’s compassion and care for this very tragic and troubling time.” C.B.
★★★★★
“Bob Kreisman did everything possible in handling the trial of this case. It was devastating that I traumatically lost my leg above the knee in this truck accident. However, it was not an easy case to win. His staff was so prepared for the trial that it was not surprising that the settlement offers continued to rise until we finally accepted the multi-million settlement while the jury was still deciding the case. My wife and I were delighted that we could secure our future with this settlement. We thank Mr. Kreisman and his incredible staff for working so hard for our benefit.” T.P.
★★★★★
“My mother died because doctors dropped the ball. I called Robert Kreisman and he immediately set up an appointment for my entire family. We met at his offices and I was very comfortable that he would do the best for my dad and my brothers. He spent hours with all of us in preparing for depositions and he hired top notch experts, all of which contributed to an incredible settlement before trial. I know that he is dedicated to his cases and particularly to the people he works for and the people who work with him. He continues to be generous in contributing annually to my mother’s memory and to make known to the public the signs and symptoms of brain tumors.” V.S.
★★★★★
“My dad was ignored and mistreated at the nursing home that we placed him in. It didn’t take long for us to realize that we made a big mistake, particularly after my dad developed these terrible bedsores. We transferred him as we were contacting Mr. Kreisman. He was referred to us by a lawyer we have known for a long time and respect his opinion. Mr. Kreisman and his staff worked tirelessly to resolve this case. We were fortunate to have his services and will recommend him to anyone.” T.J.